Transmembrane Protein 251 (TMEM251)

C14orf109 Belongs to the UPF0694 family.Chromosome14 is one of the 23 pairs of chromosomes in humans. Chromosome 14 spans about 109 million base pairs and represents between 3 and 3.5% of the total DNA in cells. Translocations involving chromosome 14 have been found in cancers of blood-forming cells, cancers of immune system cells, and several related diseases. For example, Burkitt lymphoma, a cancer of white blood cells that occurs most often in children and young adults, is related to a translocation between chromosomes 8 and 14. Another type of lymphoma, called follicular lymphoma, is often associated with a translocation between chromosomes 14 and 18. In a cancer of white blood cells called multiple myeloma, the presence of a translocation between chromosomes 4 and 14 is associated with a more aggressive form of the disease.