Chromosome 16 Open Reading Frame 13 (C16orf13)

C16orf13 is located on the short arm of chromosome 16 in humans, in the thirteenth open reading frame. There are five transcript variants of this gene, named 1, 2, 3, 4, and 7. The longest cDNA transcript (transcript variant 1) contains 854 base pairs. This transcript is composed of six exons, all of which contribute to the major superfamily included in the protein, the methyltransferases superfamily. The primary transcript of this gene is 1,919 base pairs long. The protein that this gene codes for is known as UPF0585, where UPF signals unknown protein function. There are five isoforms of this protein, corresponding to the five splice variants of the gene. The isoforms are named a, b, c, d, and g As mentioned above, the conserved domain detected in a BLAST search of this amino acid sequence is a methyltransferase superfamily.