Chromosome 16 Open Reading Frame 42 (C16orf42)

C16orf42, or chromosome 16 open reading frame 42, is a hypothetical human protein found on chromosome 16. Its protein is 312 amino acids long. and its cDNA has 1214 base pairs. The function of C16orf42 is unknown. It is predicted to be a transmembrane protein, however the cellular or subcellular membrane in which is resides is as well unknown.

C16orf42 can also be found in many other organisms, including mammals, and certain fungi and plants. It is not found in bacteria. C16orf42 is highly conserved in many of its orthologs, especially its mammalian orthologs, as high as 95% identity in Rhesus monkeys. It also has fairly high conservation in its more distant homologs, 53% identity in corn for example. It has one potential human paralog, the protein EGFL6.