Cochlin (COCH)

COCH-5B2; COCH5B2; DFNA31; DFNA9; Coagulation Factor C; Limulus Polyphemus Homolog
Cochlin (COCH)
Cochlin is highly conserved in human, mouse, and chicken, showing 94% and 79% amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells.
This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene.
Organism species: Homo sapiens (Human)
  • Protein RPJ406Hu01Recombinant Cochlin (COCH)Customize
  • AntibodyPAJ406Hu01Polyclonal Antibody to Cochlin (COCH)Customize
  • AntibodyMAJ406Hu21Monoclonal Antibody to Cochlin (COCH)Customize
  • Assay KitSEJ406HuELISA Kit for Cochlin (COCH)In Stock
  • Assay KitSCJ406HuCLIA Kit for Cochlin (COCH)Customize
Organism species: Mus musculus (Mouse)
  • Protein RPJ406Mu01Recombinant Cochlin (COCH)Customize
  • AntibodyPAJ406Mu01Polyclonal Antibody to Cochlin (COCH)Customize
  • AntibodyMAJ406Mu21Monoclonal Antibody to Cochlin (COCH)Customize
  • Assay KitSEJ406MuELISA Kit for Cochlin (COCH)Customize
  • Assay KitSCJ406MuCLIA Kit for Cochlin (COCH)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPJ406Ra01Recombinant Cochlin (COCH)Customize
  • AntibodyPAJ406Ra01Polyclonal Antibody to Cochlin (COCH)Customize
  • AntibodyMAJ406Ra21Monoclonal Antibody to Cochlin (COCH)Customize
  • Assay KitSEJ406RaELISA Kit for Cochlin (COCH)Customize
  • Assay KitSCJ406RaCLIA Kit for Cochlin (COCH)Customize
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