Complement C4-B (C4B)
CO4; CPAMD3; Basic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3; Complement component 4B, Chido blood group
Complement component 4B (Chido blood group) is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9.
Organism species: Homo sapiens (Human)
- Recombinant protein RPB305Hu01 Recombinant Complement C4-B (C4B) In Stock
- Recombinant protein RPB305Hu02 Recombinant Complement C4-B (C4B) In Stock
- Recombinant protein RPB305Hu03 Recombinant Complement C4-B (C4B) In Stock
- Polyclonal antibody PAB305Hu01 Polyclonal Antibody to Complement C4-B (C4B) In Stock
- Monoclonal antibody MAB305Hu22 Monoclonal Antibody to Complement C4-B (C4B) In Stock
- Polyclonal antibody PAB305Hu02 Polyclonal Antibody to Complement C4-B (C4B) In Stock
- Polyclonal antibody PAB305Hu03 Polyclonal Antibody to Complement C4-B (C4B) In Stock
- Monoclonal antibody MAB305Hu21 Monoclonal Antibody to Complement C4-B (C4B) In Stock
- Monoclonal antibody MAB305Hu23 Monoclonal Antibody to Complement C4-B (C4B) In Stock
- Sandwich ELISA SEB305Hu ELISA Kit for Complement C4-B (C4B) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPB305Mu01 Recombinant Complement C4-B (C4B) In Stock
- Recombinant protein RPB305Mu02 Recombinant Complement C4-B (C4B) In Stock
- Polyclonal antibody PAB305Mu01 Polyclonal Antibody to Complement C4-B (C4B) In Stock
- Labelled antibody LAB305Mu71 Biotin-Linked Polyclonal Antibody to Complement C4-B (C4B) In Stock
- Labelled antibody LAB305Mu81 FITC-Linked Polyclonal Antibody to Complement C4-B (C4B) In Stock
- Polyclonal antibody PAB305Mu02 Polyclonal Antibody to Complement C4-B (C4B) In Stock
- Sandwich ELISA SEB305Mu ELISA Kit for Complement C4-B (C4B) In Stock
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPB305Ra01 Recombinant Complement C4-B (C4B) In Stock
- Customized Service n/a Monoclonal Antibody to Complement C4-B (C4B) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Complement C4-B (C4B) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Complement C4-B (C4B) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Complement C4-B (C4B) ELISA Kit Customized Service Offer