Beta-Crosslaps (bCTx)

CrossLaps peptide is a part of the C-telopeptide of the beta 1-chain of type I collagen of bone, is a recently developed biochemical marker of bone turnover.

Serum beta-crosslaps are an established laboratory test to investigate bone metabolism. However, lytic conditions may affect the measurement of serum beta-crosslaps. the influence of proteolytic conditions on the serum concentration of beta-crosslaps is not uniform. Leukocyte lysate decreased serum beta-crosslaps while the addition of cathepsin C increased their concentration. Therefore, serum should be separated from the whole blood immediately after coagulation and stored until analysis in a deep freezer. Aliases: B-CTx; Beta CrossLaps; Beta-CTx; C-Telopeptide; C-terminal collagen crosslinks; Carboxy terminal collagen crosslinks; CTx; Soft-CTX