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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
Crumbs Homolog 1 (CRB1)
LCA8; RP12
Crumbs homolog 1 is a protein which is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. In Drosophila crumbs localizes to the stalk of the fly photoreceptor and may be a component of the molecular scaffold that controls proper development of polarity in the eye.
Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis. Alternatively spliced transcript variants have been observed but their full-length nature has yet to be determined. One small study suggests that mutations in this gene are associated with keratoconus in patients that already have Leber's congenital amaurosis.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPF775Hu01 Recombinant Crumbs Homolog 1 (CRB1) Customize
Antibodies PAF775Hu01 Polyclonal Antibody to Crumbs Homolog 1 (CRB1) Customize
MAF775Hu21 Monoclonal Antibody to Crumbs Homolog 1 (CRB1) Customize
Assay Kits SEF775Hu ELISA Kit for Crumbs Homolog 1 (CRB1) Customize
SCF775Hu CLIA Kit for Crumbs Homolog 1 (CRB1) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPF775Mu01 Recombinant Crumbs Homolog 1 (CRB1) Customize
Antibodies PAF775Mu01 Polyclonal Antibody to Crumbs Homolog 1 (CRB1) Customize
MAF775Mu21 Monoclonal Antibody to Crumbs Homolog 1 (CRB1) Customize
Assay Kits SEF775Mu ELISA Kit for Crumbs Homolog 1 (CRB1) Customize
SCF775Mu CLIA Kit for Crumbs Homolog 1 (CRB1) Customize
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME
Proteins RPF775Ra01 Recombinant Crumbs Homolog 1 (CRB1) Customize
Antibodies PAF775Ra01 Polyclonal Antibody to Crumbs Homolog 1 (CRB1) Customize
MAF775Ra21 Monoclonal Antibody to Crumbs Homolog 1 (CRB1) Customize
Assay Kits SEF775Ra ELISA Kit for Crumbs Homolog 1 (CRB1) Customize
SCF775Ra CLIA Kit for Crumbs Homolog 1 (CRB1) Customize