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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
Cyclin Dependent Kinase 3 (CDK3)
Ye et al. (2001) reported the presence of a single point mutation in the CDK3 gene from several Mus musculus strains commonly used in the laboratory. This mutation results in the replacement of a conserved tryptophan (trp187) within kinase consensus domain IX with a stop codon. The protein predicted to be encoded by this allele was truncated near the T loop, which is involved in activation by CDK-activating kinase (CCNH). This mutation also deletes motif XI, known to be required for kinase function, and is therefore expected to generate a null allele. The mutation was missing in 2 wild-mice species. The data indicated that CDK3 is not required for M. musculus development and suggested that any functional role played by CDK3 in the G1/S-phase transition is likely to be redundant with another CDK.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPD244Hu01 Recombinant Cyclin Dependent Kinase 3 (CDK3) Customize
Antibodies PAD244Hu01 Polyclonal Antibody to Cyclin Dependent Kinase 3 (CDK3) Customize
MAD244Hu21 Monoclonal Antibody to Cyclin Dependent Kinase 3 (CDK3) Customize
Assay Kits SED244Hu ELISA Kit for Cyclin Dependent Kinase 3 (CDK3) Customize
SCD244Hu CLIA Kit for Cyclin Dependent Kinase 3 (CDK3) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPD244Mu01 Recombinant Cyclin Dependent Kinase 3 (CDK3) Customize
Antibodies PAD244Mu01 Polyclonal Antibody to Cyclin Dependent Kinase 3 (CDK3) Customize
MAD244Mu21 Monoclonal Antibody to Cyclin Dependent Kinase 3 (CDK3) Customize
Assay Kits SED244Mu ELISA Kit for Cyclin Dependent Kinase 3 (CDK3) Customize
SCD244Mu CLIA Kit for Cyclin Dependent Kinase 3 (CDK3) Customize