Cyclin G Associated Kinase (GAK)

Cyclin G Associated Kinase (GAK)
In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5.Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin- coated vesicles by Hsc70 in non-neuronal cells.
Organism species: Homo sapiens (Human)
  • Protein RPD279Hu01Recombinant Cyclin G Associated Kinase (GAK)Customize
  • AntibodyPAD279Hu01Polyclonal Antibody to Cyclin G Associated Kinase (GAK)Customize
  • AntibodyMAD279Hu21Monoclonal Antibody to Cyclin G Associated Kinase (GAK)Customize
  • Assay KitSED279HuELISA Kit for Cyclin G Associated Kinase (GAK)Customize
  • Assay KitSCD279HuCLIA Kit for Cyclin G Associated Kinase (GAK)Customize
Organism species: Mus musculus (Mouse)
  • Protein RPD279Mu01Recombinant Cyclin G Associated Kinase (GAK)Customize
  • AntibodyPAD279Mu01Polyclonal Antibody to Cyclin G Associated Kinase (GAK)Customize
  • AntibodyMAD279Mu21Monoclonal Antibody to Cyclin G Associated Kinase (GAK)Customize
  • Assay KitSED279MuELISA Kit for Cyclin G Associated Kinase (GAK)Customize
  • Assay KitSCD279MuCLIA Kit for Cyclin G Associated Kinase (GAK)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPD279Ra01Recombinant Cyclin G Associated Kinase (GAK)Customize
  • AntibodyPAD279Ra01Polyclonal Antibody to Cyclin G Associated Kinase (GAK)Customize
  • AntibodyMAD279Ra21Monoclonal Antibody to Cyclin G Associated Kinase (GAK)Customize
  • Assay KitSED279RaELISA Kit for Cyclin G Associated Kinase (GAK)Customize
  • Assay KitSCD279RaCLIA Kit for Cyclin G Associated Kinase (GAK)Customize
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