Cyclin N-Terminal Domain Containing Protein 1 (CNTD1)

CNTD1, Contains 1 cyclin N-terminal domain. Cyclins are generally very different from each other in primary structure, or amino acid sequence. The similarity between members of the cyclin family are similar in the 100 amino acids that make up the cyclin box. Cyclins contain two domains of similar all-α fold, the first located at the N-terminus and the second at the C-terminus. All cyclins are believed to contain a similar tertiary structure of two compact domains of 5 α helices. The first of which is the conserved cyclin box, outside of which cyclins are divergent. For example, the amino-terminal regions of S and M cyclins contain short destruction-box motifs that target these proteins for proteolysis in mitosis. In the context of diethyl maleate, Cyclin, N-terminal has rank 3 out of 11556 'Domain' concepts (top 0.03%) in BioGraph's knowledge base.