DNA Methyltransferase 1 (DNMT1)
CXXC9; DNMT; MCMT; Cytosine-5 DNA Methyltransferase 1; CXXC-type zinc finger protein 9; DNA methyltransferase HsaI
DNA (cytosine-5)-methyltransferases (DNMTs), such as DNMT1, maintain patterns of methylated cytosine residues in the mammalian genome. Genomic methylation patterns are reshaped during gametogenesis and early development and undergo programmed alterations during cellular differentiation. Methylation patterns are responsible for the repression of parasitic sequence elements and the expression status of genes subject to genomic imprinting and X inactivation. Faithful maintenance of methylation patterns is required for normal mammalian development, and aberrant methylation patterns are associated with certain human tumors and developmental abnormalities.A DNMT1 enzyme is thought to be responsible for most of the maintenance as well as the de novo methylation activities occurring in the somatic cells of vertebrates.
Organism species: Homo sapiens (Human)
- Recombinant protein RPJ244Hu01 Recombinant DNA Methyltransferase 1 (DNMT1) In Stock
- Polyclonal antibody PAJ244Hu01 Polyclonal Antibody to DNA Methyltransferase 1 (DNMT1) In Stock
- Monoclonal antibody MAJ244Hu21 Monoclonal Antibody to DNA Methyltransferase 1 (DNMT1) In Stock
- Sandwich ELISA SEJ244Hu ELISA Kit for DNA Methyltransferase 1 (DNMT1) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPJ244Mu01 Recombinant DNA Methyltransferase 1 (DNMT1) In Stock
- Recombinant protein RPJ244Mu02 Recombinant DNA Methyltransferase 1 (DNMT1) In Stock
- Polyclonal antibody PAJ244Mu01 Polyclonal Antibody to DNA Methyltransferase 1 (DNMT1) In Stock
- Polyclonal antibody PAJ244Mu02 Polyclonal Antibody to DNA Methyltransferase 1 (DNMT1) In Stock
- Sandwich ELISA SEJ244Mu ELISA Kit for DNA Methyltransferase 1 (DNMT1) In Stock
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant DNA Methyltransferase 1 (DNMT1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to DNA Methyltransferase 1 (DNMT1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to DNA Methyltransferase 1 (DNMT1) Polyclonal Antibody Customized Service Offer
- Sandwich ELISA SEJ244Ra ELISA Kit for DNA Methyltransferase 1 (DNMT1) In Stock