Dehydrogenase/Reductase SDR Family, X-Linked (DHRSX)

DHRSX is an enzyme encoded by the pseudoautosomal DHRSX gene.DHRSX is a member of the short-chain dehydrogenase family of oxidoreductase enzymes.

The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases. As the first member of this family to be characterised was Drosophila alcohol dehydrogenase, this family used to be called 'insect-type', or 'short-chain' alcohol dehydrogenases. Most member of this family are proteins of about 250 to 300 amino acid residues. Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate.