Differentially Expressed In FDCP 8 (DEF8)

DEF8, Belongs to the DEF8 family.Contains 2 phorbol-ester/DAG-type zinc fingers.Zinc fingers are small protein structural motifs that can coordinate one or more zinc ions to help stabilize their folds. They can be classified into several different structural families and typically function as interaction modules that bind DNA, RNA, proteins, or small molecules.Zinc fingers coordinate zinc ions with a combination of cysteine and histidine residues. They can be classified by the type and order of these zinc coordinating residues. A more systematic method classifies them into different "fold groups" based on the overall shape of the protein backbone in the folded domain. The most common "fold groups" of zinc fingers are the Cys₂His₂-like (the "classic zinc finger"), treble clef, and zinc ribbon.