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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
Dystrobrevin Binding Protein 1 (DTNBP1)
DBND; HPS7; My031; SDY; Dysbindin
Dysbindin is a protein constituent of the dystrophin-associated protein complex (DPC) of skeletal muscle cells. It is also a part of BLOC-1, or biogenesis of lysosome-related organelles complex 1. Dysbindin was discovered by the research group of Derek Blake via yeast two-hybrid screening for binding partners of α-dystrobrevin. In addition, dysbindin is found in neural tissue of the brain, particularly in axon bundles and especially in certain axon terminals, notably mossy fiber synaptic terminals in the cerebellum and hippocampus.Probable dysbindin-related mechanisms causing brain dysfunction are not fully known, but in one study, schizophrenic patients carrying the high-risk haplotype demonstrated visual processing deficits. In another work, damping down the DTNBP1 expression led to an increase in cell surface dopamine D2-receptor levels.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPC444Hu01 Recombinant Dystrobrevin Binding Protein 1 (DTNBP1) Customize
Antibodies PAC444Hu01 Polyclonal Antibody to Dystrobrevin Binding Protein 1 (DTNBP1) Customize
MAC444Hu21 Monoclonal Antibody to Dystrobrevin Binding Protein 1 (DTNBP1) Customize
Assay Kits SEC444Hu ELISA Kit for Dystrobrevin Binding Protein 1 (DTNBP1) Customize
SCC444Hu CLIA Kit for Dystrobrevin Binding Protein 1 (DTNBP1) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPC444Mu01 Recombinant Dystrobrevin Binding Protein 1 (DTNBP1) Customize
Antibodies PAC444Mu01 Polyclonal Antibody to Dystrobrevin Binding Protein 1 (DTNBP1) Customize
MAC444Mu21 Monoclonal Antibody to Dystrobrevin Binding Protein 1 (DTNBP1) Customize
Assay Kits SEC444Mu ELISA Kit for Dystrobrevin Binding Protein 1 (DTNBP1) Customize
SCC444Mu CLIA Kit for Dystrobrevin Binding Protein 1 (DTNBP1) Customize