Dystrophin (DMD)

CMD3B; Muscular Dystrophy,Duchenne And Becker Types
Dystrophin (DMD)
Dystrophin is a rod-shaped cytoplasmic protein, and a vital part of a protein complex that connects the cytoskeleton of a muscle fiber to the surrounding extracellular matrix through the cell membrane. This complex is variously known as the costamere or the dystrophin-associated protein complex. Many muscle proteins, such as α-dystrobrevin, syncoilin, synemin, sarcoglycan, dystroglycan, and sarcospan, colocalize with dystrophin at the costamere. As of 2007, dystrophin is the longest gene known, covering 2.4 megabases (0.08% of the human genome) at locus Xp21. The primary transcript measures about 2,400 kilobases and takes 16 hours to transcribe, the mature mRNA measures 14.0 kilobases. The 79 exons code for a protein of over 3500 amino acid residues.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
Organism species: Rattus norvegicus (Rat)
  • Protein RPB503Ra01Recombinant Dystrophin (DMD)Customize
  • AntibodyPAB503Ra01Polyclonal Antibody to Dystrophin (DMD)Customize
  • AntibodyMAB503Ra21Monoclonal Antibody to Dystrophin (DMD)Customize
  • Assay KitSEB503RaELISA Kit for Dystrophin (DMD)Customize
  • Assay KitSCB503RaCLIA Kit for Dystrophin (DMD)Customize
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