Endothelin 3 (EDN3)

ET3; PPET3; Preproendothelin-3
Endothelin 3 (EDN3)
Endothelin-3 is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.
Organism species: Homo sapiens (Human)
  • Protein RPC465Hu01Recombinant Endothelin 3 (EDN3)Customize
  • AntibodyPAC465Hu01Polyclonal Antibody to Endothelin 3 (EDN3)Customize
  • AntibodyMAC465Hu21Monoclonal Antibody to Endothelin 3 (EDN3)Customize
  • Assay KitSEC465HuELISA Kit for Endothelin 3 (EDN3)Customize
  • Assay KitSCC465HuCLIA Kit for Endothelin 3 (EDN3)Customize
Organism species: Mus musculus (Mouse)
  • Protein RPC465Mu01Recombinant Endothelin 3 (EDN3)Customize
  • AntibodyPAC465Mu01Polyclonal Antibody to Endothelin 3 (EDN3)Customize
  • AntibodyMAC465Mu21Monoclonal Antibody to Endothelin 3 (EDN3)Customize
  • Assay KitSEC465MuELISA Kit for Endothelin 3 (EDN3)Customize
  • Assay KitSCC465MuCLIA Kit for Endothelin 3 (EDN3)Customize
Organism species: Rattus norvegicus (Rat)
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