Enterotoxin B (EntB)

Enterotoxin type B is an enterotoxin produced by the gram-positive bacteria Staphylococcus aureus. It is a common cause of food poisoning, with severe diarrhea, nausea and intestinal cramping often starting within a few hours of ingestion. Being quite stable, the toxin may remain active even after the contaminating bacteria are killed. It can withstand boiling at 100°C for a few minutes. Gastroenteritis occurs because SEB is a superantigen, causing the immune system to release a large amount of cytokines that lead to significant inflammation. The protein domain found in this bacteria causes infections due to its multiple antibiotic resistant nature. The function of this protein is to facilitate the infection of the host organism. It is a virulence factor designed to induce pathogenesis One of the major virulence exotoxins is the toxic shock syndrome toxin (TSST), which is secreted by the organism upon successful invasion.