Epididymal Protein 3B (EDDM3B)
FAM12B; HE3-BETA; Family With Sequence Similarity 12,Member B; Human epididymis-specific protein 3-beta
Testicular sperm are morphologically differentiated but are not progressively motile nor able to fertilize an egg. Post-testicular maturation requires exposure of spermatozoa to the microenvironment of the epididymal lumen. Spermatozoa undergo extensive changes in the epididymis, including enzymatic modifications, loss of pre-existing components and addition of new glycoproteins from epididymal secretions. These modifying proteins and enzymes are synthesized by epithelial cells lining the epididymal duct and secreted apically into the lumen, where they come into contact with, and may be absorbed onto, the sperm membranes. The proteins encoded by the genes in this cluster are synthesized and secreted by epididymal epithelial cells.RNase protection assays showed that both HE3A and HE3B transcripts are expressed in human epididymis.
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
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Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Epididymal Protein 3B (EDDM3B) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Epididymal Protein 3B (EDDM3B) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Epididymal Protein 3B (EDDM3B) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Epididymal Protein 3B (EDDM3B) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Epididymal Protein 3B (EDDM3B) ELISA Kit Customized Service Offer