Ewing Sarcoma Breakpoint Region 1 (EWSR1)

EWS; RNA-binding protein EWS; EWS oncogene
Ewing Sarcoma Breakpoint Region 1 (EWSR1)
EWSR1 encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11;22)(q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors.
Organism species: Homo sapiens (Human)
  • Protein RPJ731Hu01Recombinant Ewing Sarcoma Breakpoint Region 1 (EWSR1)Customize
  • AntibodyPAJ731Hu01Polyclonal Antibody to Ewing Sarcoma Breakpoint Region 1 (EWSR1)Customize
  • AntibodyMAJ731Hu21Monoclonal Antibody to Ewing Sarcoma Breakpoint Region 1 (EWSR1)Customize
  • Assay KitSEJ731HuELISA Kit for Ewing Sarcoma Breakpoint Region 1 (EWSR1)Customize
  • Assay KitSCJ731HuCLIA Kit for Ewing Sarcoma Breakpoint Region 1 (EWSR1)Customize
Organism species: Mus musculus (Mouse)
  • Protein RPJ731Mu01Recombinant Ewing Sarcoma Breakpoint Region 1 (EWSR1)Customize
  • AntibodyPAJ731Mu01Polyclonal Antibody to Ewing Sarcoma Breakpoint Region 1 (EWSR1)Customize
  • AntibodyMAJ731Mu21Monoclonal Antibody to Ewing Sarcoma Breakpoint Region 1 (EWSR1)Customize
  • Assay KitSEJ731MuELISA Kit for Ewing Sarcoma Breakpoint Region 1 (EWSR1)Customize
  • Assay KitSCJ731MuCLIA Kit for Ewing Sarcoma Breakpoint Region 1 (EWSR1)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPJ731Ra01Recombinant Ewing Sarcoma Breakpoint Region 1 (EWSR1)Customize
  • AntibodyPAJ731Ra01Polyclonal Antibody to Ewing Sarcoma Breakpoint Region 1 (EWSR1)Customize
  • AntibodyMAJ731Ra21Monoclonal Antibody to Ewing Sarcoma Breakpoint Region 1 (EWSR1)Customize
  • Assay KitSEJ731RaELISA Kit for Ewing Sarcoma Breakpoint Region 1 (EWSR1)Customize
  • Assay KitSCJ731RaCLIA Kit for Ewing Sarcoma Breakpoint Region 1 (EWSR1)Customize
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