Family With Sequence Similarity 43, Member A (FAM43A)

FAM43A belongs to the FAM43 subfamily. The acronym means "family with sequence similarity 43, member A". The specific function of FAM43A is currently unknown, and the gene has only been characterized in cDNA assays. FAM43A is located on chromosome 3 at location 3q29. It encodes a 3182 base pair mRNA which possesses one Pleckstrin homology-like domain. The mRNA translates into LOC131583, a hydrophilic protein 423 amino acids long. The protein has been predicted to localize in the nucleus, and possesses a cut signal peptide at amino acid 21.The FAM43A gene is conserved through a broad range of vertebrates. Conservation is extremely high among primates, remaining significant among species as distant as zebrafish.