Fission 1 (FIS1)
CGI-135; TTC11; Tetratricopeptide Repeat Domain 11; Mitochondrial fission 1 protein
The balance between fission and fusion regulates the morphology of mitochondria. TTC11 is a component of a mitochondrial complex that promotes mitochondrial fission.
The deduced 152-amino acid protein contains a central leucine zipper, a coiled-coil region, and a C-terminal transmembrane domain. It also contains a region showing high interspecies homology and a putative tetratricopeptide repeat. Immunocytochemical analysis of HeLa cells detected endogenous FIS1 expression in mitochondria. Protease treatment indicated that FIS1 is expressed at the outer mitochondrial membrane. Transfection of a C-terminal truncated FIS1 resulted in cytoplasmic expression, indicating that the C terminus is required for mitochondrial localization.
Organism species: Homo sapiens (Human)
- Recombinant protein RPJ105Hu01 Recombinant Fission 1 (FIS1) In Stock
- Polyclonal antibody PAJ105Hu01 Polyclonal Antibody to Fission 1 (FIS1) In Stock
- Monoclonal antibody MAJ105Hu21 Monoclonal Antibody to Fission 1 (FIS1) In Stock
- Monoclonal antibody MAJ105Hu22 Monoclonal Antibody to Fission 1 (FIS1) In Stock
- Sandwich ELISA SEJ105Hu ELISA Kit for Fission 1 (FIS1) In Stock
Organism species: Mus musculus (Mouse)
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Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Fission 1 (FIS1) Recombinant Protein Customized Service Offer
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- Customized Service n/a Polyclonal Antibody to Fission 1 (FIS1) Polyclonal Antibody Customized Service Offer
- Sandwich ELISA SEJ105Ra ELISA Kit for Fission 1 (FIS1) In Stock