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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
Fusion (FUS)
CHOP; ALS6; FUS-CHOP; FUS1; TLS; hnRNP-P2; RNA-Binding Protein FUS; Amyotrophic Lateral Sclerosis 6; Heterogeneous Nuclear Ribonucleoprotein P2
FUS is a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. The N-terminal end of FUS appears to be involved in transcriptional activation, while the C-terminal end is involved in protein and RNA binding. In addition recognition sites for the transcription factors AP2, GCF, Sp1 have been identified in FUS.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPC260Hu01 Recombinant Fusion (FUS) Customize
Antibodies MAC260Hu22 Monoclonal Antibody to Fusion (FUS) Customize
PAC260Hu01 Polyclonal Antibody to Fusion (FUS) Customize
Assay Kits SEC260Hu ELISA Kit for Fusion (FUS) In Stock
SCC260Hu CLIA Kit for Fusion (FUS) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPC260Mu01 Recombinant Fusion (FUS) In Stock
RPC260Mu02 Recombinant Fusion (FUS) Customize
Antibodies PAC260Mu01 Polyclonal Antibody to Fusion (FUS) In Stock
PAC260Mu02 Polyclonal Antibody to Fusion (FUS) Customize
PAC260Mu71 Biotin-Linked Antibody to Fusion (FUS) Customize
PAC260Mu81 FITC-Linked Antibody to Fusion (FUS) Customize
MAC260Mu21 Monoclonal Antibody to Fusion (FUS) Customize
Assay Kits SEC260Mu ELISA Kit for Fusion (FUS) In Stock
SCC260Mu CLIA Kit for Fusion (FUS) Customize
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME
Proteins RPC260Ra01 Recombinant Fusion (FUS) Customize
Antibodies PAC260Ra01 Polyclonal Antibody to Fusion (FUS) Customize
MAC260Ra21 Monoclonal Antibody to Fusion (FUS) Customize
Assay Kits SEC260Ra ELISA Kit for Fusion (FUS) Customize
SCC260Ra CLIA Kit for Fusion (FUS) Customize