G Protein Gamma 5 (GNg5)

G proteins are trimeric (alpha-beta-gamma) membrane-associated proteins that regulate flow of information from cell surface receptors to a variety of internal metabolic effectors. Interaction of a G protein with its activated receptor promotes exchange of GTP for GDP that is bound to the alpha subunit. The alpha-GTP complex dissociates from the beta-gamma heterodimer so that the subunits, in turn, may interact with and regulate effector molecules.At base position 957 of the cDNA for native chitobiase, which would be the 3-prime end of exon 6 of the chitobiase gene, there was fused in-frame a sequence that represented exons 2 and 3 from the gamma-5 gene. Exons 2 and 3, respectively, code for the carboxyl-end of the gamma-5 protein and the 3-prime untranslated portion of its mRNA.