GATA Binding Protein 3 (GATA3)

HDR; Trans-acting T-cell-specific transcription factor GATA-3
GATA Binding Protein 3 (GATA3)
Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all 4 TCR genes. GATA3 had been shown in the chicken to be an enhancer-binding protein containing a zinc finger domain. GATA3 mRNA was demonstrated by Northern blot analysis in T cells but not in B cells, macrophages, or HeLa cell lines. GATA3 was abundantly expressed in the T-lymphocyte lineage and was thought to participate in T-cell receptor gene activation through binding to enhancers. Labastie et al. (1994) cloned the human gene and the 5-prime end of the mouse gene. The 2 zinc fingers of GATA3 are encoded by 2 separate exons highly conserved with those of GATA1, but no other structural homologies between the 2 genes could be found.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
  • Protein RPA410Mu01Recombinant GATA Binding Protein 3 (GATA3)Customize
  • AntibodyPAA410Mu01Polyclonal Antibody to GATA Binding Protein 3 (GATA3)Customize
  • AntibodyMAA410Mu21Monoclonal Antibody to GATA Binding Protein 3 (GATA3)Customize
  • Assay KitSEA410MuELISA Kit for GATA Binding Protein 3 (GATA3)Customize
  • Assay KitSCA410MuCLIA Kit for GATA Binding Protein 3 (GATA3)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPA410Ra01Recombinant GATA Binding Protein 3 (GATA3)Customize
  • AntibodyPAA410Ra01Polyclonal Antibody to GATA Binding Protein 3 (GATA3)Customize
  • AntibodyMAA410Ra21Monoclonal Antibody to GATA Binding Protein 3 (GATA3)Customize
  • Assay KitSEA410RaELISA Kit for GATA Binding Protein 3 (GATA3)Customize
  • Assay KitSCA410RaCLIA Kit for GATA Binding Protein 3 (GATA3)Customize
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