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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
GM2 Ganglioside Activator (GM2A)
SAP-3; Cerebroside Sulfate Activator Protein; Sphingolipid Activator Protein 3
GM2A is a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme β-hexosaminidase A. β-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines.
GM2A is a lipid transfer protein that stimulates the enzymatic processing of gangliosides, and also T-cell activation through lipid presentation. This protein binds molecules of ganglioside GM2, extracts them from membranes, and presents them to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.It was identified as a member of ML domain family of proteins involved in innate immunity and lipid metabolism in the SMART database.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPL122Hu01 Recombinant GM2 Ganglioside Activator (GM2A) Customize
Antibodies MAL122Hu21 Monoclonal Antibody to GM2 Ganglioside Activator (GM2A) Customize
PAL122Hu01 Polyclonal Antibody to GM2 Ganglioside Activator (GM2A) Customize
Assay Kits SEL122Hu ELISA Kit for GM2 Ganglioside Activator (GM2A) In Stock
SCL122Hu CLIA Kit for GM2 Ganglioside Activator (GM2A) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPL122Mu01 Recombinant GM2 Ganglioside Activator (GM2A) Customize
Antibodies PAL122Mu01 Polyclonal Antibody to GM2 Ganglioside Activator (GM2A) Customize
MAL122Mu21 Monoclonal Antibody to GM2 Ganglioside Activator (GM2A) Customize
Assay Kits SEL122Mu ELISA Kit for GM2 Ganglioside Activator (GM2A) Customize
SCL122Mu CLIA Kit for GM2 Ganglioside Activator (GM2A) Customize
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME
Proteins RPL122Ra01 Recombinant GM2 Ganglioside Activator (GM2A) Customize
Antibodies PAL122Ra01 Polyclonal Antibody to GM2 Ganglioside Activator (GM2A) Customize
MAL122Ra21 Monoclonal Antibody to GM2 Ganglioside Activator (GM2A) Customize
Assay Kits SEL122Ra ELISA Kit for GM2 Ganglioside Activator (GM2A) Customize
SCL122Ra CLIA Kit for GM2 Ganglioside Activator (GM2A) Customize