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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
GTP Binding Protein Overexpressed In Skeletal Muscle (GEM)
KIR; Kinase-Inducible Ras-Like Protein
GEM and RAD, the product of a gene overexpressed in skeletal muscle and in individuals with type II diabetes mellitus, constitute a new family of RAS-related GTP-binding proteins. The distinct structural features of this family include the GTP-binding motif, extensive amino- and carboxyl-terminal extensions beyond the RAS-related domain, and a motif that determines membrane association. GEM was transiently expressed in human peripheral blood T cells in response to mitogen stimulation; the protein was phosphorylated on tyrosine residues and localized to the cytosolic face of the plasma membrane. Deregulated GEM expression prevented proliferation of normal and transformed NIH 3T3 cells. These results suggested that GEM is a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPJ042Hu01 Recombinant GTP Binding Protein Overexpressed In Skeletal Muscle (GEM) Customize
Antibodies PAJ042Hu01 Polyclonal Antibody to GTP Binding Protein Overexpressed In Skeletal Muscle (GEM) Customize
MAJ042Hu21 Monoclonal Antibody to GTP Binding Protein Overexpressed In Skeletal Muscle (GEM) Customize
Assay Kits SEJ042Hu ELISA Kit for GTP Binding Protein Overexpressed In Skeletal Muscle (GEM) Customize
SCJ042Hu CLIA Kit for GTP Binding Protein Overexpressed In Skeletal Muscle (GEM) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPJ042Mu01 Recombinant GTP Binding Protein Overexpressed In Skeletal Muscle (GEM) Customize
Antibodies PAJ042Mu01 Polyclonal Antibody to GTP Binding Protein Overexpressed In Skeletal Muscle (GEM) Customize
MAJ042Mu21 Monoclonal Antibody to GTP Binding Protein Overexpressed In Skeletal Muscle (GEM) Customize
Assay Kits SEJ042Mu ELISA Kit for GTP Binding Protein Overexpressed In Skeletal Muscle (GEM) Customize
SCJ042Mu CLIA Kit for GTP Binding Protein Overexpressed In Skeletal Muscle (GEM) Customize