General Transcription Factor IIH, Polypeptide 5 (GTF2H5)

TTD; TFB5; TGF2H5; TTD-A; TTDA; C6orf175; DNA Repair Syndrome Trichothiodystrophy Group A; TFIIH basal transcription factor complex TTD-A subunit
General Transcription Factor IIH, Polypeptide 5 (GTF2H5)
General Transcription Factor IIH,Polypeptide 5 is a subunit of transcription/repair factor TFIIH, which functions in gene transcription and DNA repair. This protein stimulates ERCC3/XPB ATPase activity to trigger DNA opening during DNA repair, and is implicated in regulating cellular levels of TFIIH. Mutations in this gene result in trichothiodystrophy, complementation group A.
This protein, called TFB5, is a core component of yeast general transcription and DNA repair factor IIH (TFIIH). Database screening identified a human homolog of 71 amino acids that shares 28% identity with the yeast protein. Giglia-Mari et al. (2004) cloned the human cDNA corresponding to the TFB5 gene from primary fibroblasts.
Organism species: Homo sapiens (Human)
  • Protein RPD900Hu01Recombinant General Transcription Factor IIH, Polypeptide 5 (GTF2H5)Customize
  • AntibodyPAD900Hu01Polyclonal Antibody to General Transcription Factor IIH, Polypeptide 5 (GTF2H5)Customize
  • AntibodyMAD900Hu21Monoclonal Antibody to General Transcription Factor IIH, Polypeptide 5 (GTF2H5)Customize
  • Assay KitSED900HuELISA Kit for General Transcription Factor IIH, Polypeptide 5 (GTF2H5)Customize
  • Assay KitSCD900HuCLIA Kit for General Transcription Factor IIH, Polypeptide 5 (GTF2H5)Customize
Organism species: Mus musculus (Mouse)
  • Protein RPD900Mu01Recombinant General Transcription Factor IIH, Polypeptide 5 (GTF2H5)Customize
  • AntibodyPAD900Mu01Polyclonal Antibody to General Transcription Factor IIH, Polypeptide 5 (GTF2H5)Customize
  • AntibodyMAD900Mu21Monoclonal Antibody to General Transcription Factor IIH, Polypeptide 5 (GTF2H5)Customize
  • Assay KitSED900MuELISA Kit for General Transcription Factor IIH, Polypeptide 5 (GTF2H5)Customize
  • Assay KitSCD900MuCLIA Kit for General Transcription Factor IIH, Polypeptide 5 (GTF2H5)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPD900Ra01Recombinant General Transcription Factor IIH, Polypeptide 5 (GTF2H5)Customize
  • AntibodyPAD900Ra01Polyclonal Antibody to General Transcription Factor IIH, Polypeptide 5 (GTF2H5)Customize
  • AntibodyMAD900Ra21Monoclonal Antibody to General Transcription Factor IIH, Polypeptide 5 (GTF2H5)Customize
  • Assay KitSED900RaELISA Kit for General Transcription Factor IIH, Polypeptide 5 (GTF2H5)Customize
  • Assay KitSCD900RaCLIA Kit for General Transcription Factor IIH, Polypeptide 5 (GTF2H5)Customize
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