Glycogen Debranching Enzyme (AGL)

GDE; Amylo-1,6-Glucosidase; 4-Alpha-Glucanotransferase; Glycogen debrancher; 4-alpha-glucanotransferase; Oligo-1,4-1,4-glucantransferase; Dextrin 6-alpha-D-glucosidase
Glycogen Debranching Enzyme (AGL)
Debranching enzymes are responsible for transferring three glucose subunits of glycogen from one parallel chain to another. Afterwards, the donator branch will contain only one glucose residue with alpha-1,6 linkage. This remaining residue is in turn cut by alpha-1,6 glucosidase. This two step process is the general process by which the debranching enzymes "straighten out" glycogen into an unbranched glucose polymer.This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in this gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing.
Organism species: Homo sapiens (Human)
  • Protein RPD189Hu01Recombinant Glycogen Debranching Enzyme (AGL)Customize
  • AntibodyPAD189Hu01Polyclonal Antibody to Glycogen Debranching Enzyme (AGL)Customize
  • AntibodyMAD189Hu21Monoclonal Antibody to Glycogen Debranching Enzyme (AGL)Customize
  • Assay KitSED189HuELISA Kit for Glycogen Debranching Enzyme (AGL)Customize
  • Assay KitSCD189HuCLIA Kit for Glycogen Debranching Enzyme (AGL)Customize
Organism species: Mus musculus (Mouse)
  • Protein RPD189Mu01Recombinant Glycogen Debranching Enzyme (AGL)Customize
  • AntibodyPAD189Mu01Polyclonal Antibody to Glycogen Debranching Enzyme (AGL)Customize
  • AntibodyMAD189Mu21Monoclonal Antibody to Glycogen Debranching Enzyme (AGL)Customize
  • Assay KitSED189MuELISA Kit for Glycogen Debranching Enzyme (AGL)Customize
  • Assay KitSCD189MuCLIA Kit for Glycogen Debranching Enzyme (AGL)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPD189Ra01Recombinant Glycogen Debranching Enzyme (AGL)Customize
  • AntibodyPAD189Ra01Polyclonal Antibody to Glycogen Debranching Enzyme (AGL)Customize
  • AntibodyMAD189Ra21Monoclonal Antibody to Glycogen Debranching Enzyme (AGL)Customize
  • Assay KitSED189RaELISA Kit for Glycogen Debranching Enzyme (AGL)Customize
  • Assay KitSCD189RaCLIA Kit for Glycogen Debranching Enzyme (AGL)Customize
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