Growth Hormone Regulated TBC Protein 1 (GRTP1)
TBC1D6; TBC1 domain family member 6
Grtp1, a novel gene regulated by growth hormone, contains the TBC signature motif of GTPase activator proteins of Rab-like small GTPases. Northern blot analysis revealed a 1.3 kb major mRNA species, most abundant in testes. TaqMan assay confirmed that in the mouse, Grtp1 is expressed at highest levels in testes, with lesser abundance in intestine, kidney, lung, and liver. In the testis, expression of Grtp1 significantly increases post-pubertally. Administration of GH to mice increased levels of GRTP1 mRNA in testes (140%), but decreased GRTP1 mRNA abundance in kidney (50%) and liver (25%). Grtp1 was localized to mouse proximal chromosome 8. Orthologs of this protein are present in human, mouse, rat, and drosophila suggesting that GRTP1 has an important biological role(s).
Organism species: Homo sapiens (Human)
- Customized Service n/a Recombinant Growth Hormone Regulated TBC Protein 1 (GRTP1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Growth Hormone Regulated TBC Protein 1 (GRTP1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Growth Hormone Regulated TBC Protein 1 (GRTP1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Growth Hormone Regulated TBC Protein 1 (GRTP1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Growth Hormone Regulated TBC Protein 1 (GRTP1) ELISA Kit Customized Service Offer
Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant Growth Hormone Regulated TBC Protein 1 (GRTP1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Growth Hormone Regulated TBC Protein 1 (GRTP1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Growth Hormone Regulated TBC Protein 1 (GRTP1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Growth Hormone Regulated TBC Protein 1 (GRTP1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Growth Hormone Regulated TBC Protein 1 (GRTP1) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Growth Hormone Regulated TBC Protein 1 (GRTP1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Growth Hormone Regulated TBC Protein 1 (GRTP1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Growth Hormone Regulated TBC Protein 1 (GRTP1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Growth Hormone Regulated TBC Protein 1 (GRTP1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Growth Hormone Regulated TBC Protein 1 (GRTP1) ELISA Kit Customized Service Offer