Hepatocyte Nuclear Factor 6 Alpha (HNF6a)
ONECUT2; OC-2; One Cut Domain,Family Member 2; One cut homeobox 2; Transcription factor ONECUT-2
HNF6a encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation. This CCDS representation uses the 5'-most in-frame start codon, which is conserved in other vertebrates, including mouse, opossum, pig and zebrafish. An alternative downstream start codon, which has a stronger Kozak signal, also exists. It is possible that leaky scanning by ribosomes would allow the downstream start codon to be used, at least some of the time. The use of the downstream start codon would result in a protein that is 20 aa shorter at the N-terminus. There is no experimental evidence showing which start codon is preferentially used in vivo.
Organism species: Homo sapiens (Human)
- Customized Service n/a Recombinant Hepatocyte Nuclear Factor 6 Alpha (HNF6a) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Hepatocyte Nuclear Factor 6 Alpha (HNF6a) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Hepatocyte Nuclear Factor 6 Alpha (HNF6a) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Hepatocyte Nuclear Factor 6 Alpha (HNF6a) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Hepatocyte Nuclear Factor 6 Alpha (HNF6a) ELISA Kit Customized Service Offer
Organism species: Mus musculus (Mouse)
- Customized Service n/a Recombinant Hepatocyte Nuclear Factor 6 Alpha (HNF6a) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Hepatocyte Nuclear Factor 6 Alpha (HNF6a) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Hepatocyte Nuclear Factor 6 Alpha (HNF6a) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Hepatocyte Nuclear Factor 6 Alpha (HNF6a) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Hepatocyte Nuclear Factor 6 Alpha (HNF6a) ELISA Kit Customized Service Offer