Hermansky Pudlak Syndrome Protein 6 (HPS6)

Ru; Ruby-eye protein homolog
Hermansky Pudlak Syndrome Protein 6 (HPS6)
In mice there are at least 16 naturally occurring hypopigmentation models of Hermansky-Pudlak syndrome (HPS), and 9 of these have been characterized at the molecular level. Zhang et al. (2003) used positional candidate and transgenic rescue approaches to identify the genes mutated in ruby-eye-2 (ru2) and ruby-eye (ru), 2 'mimic' mouse models of HPS. They determined that these genes are orthologs of the human genes mutated in individuals with HPS5 and HPS6, respectively. Both genes are found only in higher eukaryotes. The human ru ortholog contains 775 amino acids and is 80% identical to the mouse protein. Northern blot analysis of mouse tissues detected a 2.6-kb ru transcript in all tissues tested, with lowest expression in skeletal muscle.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
  • Protein RPN696Mu01Recombinant Hermansky Pudlak Syndrome Protein 6 (HPS6)Customize
  • AntibodyPAN696Mu01Polyclonal Antibody to Hermansky Pudlak Syndrome Protein 6 (HPS6)Customize
  • AntibodyMAN696Mu21Monoclonal Antibody to Hermansky Pudlak Syndrome Protein 6 (HPS6)Customize
  • Assay KitSEN696MuELISA Kit for Hermansky Pudlak Syndrome Protein 6 (HPS6)Customize
  • Assay KitSCN696MuCLIA Kit for Hermansky Pudlak Syndrome Protein 6 (HPS6)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPN696Ra01Recombinant Hermansky Pudlak Syndrome Protein 6 (HPS6)Customize
  • AntibodyPAN696Ra01Polyclonal Antibody to Hermansky Pudlak Syndrome Protein 6 (HPS6)Customize
  • AntibodyMAN696Ra21Monoclonal Antibody to Hermansky Pudlak Syndrome Protein 6 (HPS6)Customize
  • Assay KitSEN696RaELISA Kit for Hermansky Pudlak Syndrome Protein 6 (HPS6)Customize
  • Assay KitSCN696RaCLIA Kit for Hermansky Pudlak Syndrome Protein 6 (HPS6)Customize
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