High Molecular Weight Kininogen (HMWK)
Williams-Fitzgerald-Flaujeac Factor; Fitzgerald Factor; HMWK-Kallikrein Factor
High-molecular-weight kininogen (HMWK), is a protein from the blood coagulation system as well as the kinin-kallikrein system. It is a protein that adsorbs to the surface of biomaterials that come in contact with blood in vivo. This protein circulates throughout the blood and quickly adsorbs to the material surfaces.
HMWK is one of the early participants of the intrinsic pathway of coagulation, together with Factor XII (Hageman factor) and prekallikrein. It is 626 amino acids long, and weighs 88 to 120 kDa (dependent on glycosylation). The kininogen is not enzymatically active, and functions only as a cofactor for the activation of kallikrein and Hageman factor. It is also necessary for the activation of factor XI by factor XIIa. The histidine-rich region (amino acids 420 to 510) participates most strongly in coagulation.
Organism species: Homo sapiens (Human)
- Recombinant protein RPB805Hu01 Recombinant High Molecular Weight Kininogen (HMWK) In Stock
- Recombinant protein RPB805Hu02 Recombinant High Molecular Weight Kininogen (HMWK) In Stock
- Polyclonal antibody PAB805Hu01 Polyclonal Antibody to High Molecular Weight Kininogen (HMWK) In Stock
- Polyclonal antibody PAB805Hu02 Polyclonal Antibody to High Molecular Weight Kininogen (HMWK) In Stock
- Labelled antibody LAB805Hu71 Biotin-Linked Polyclonal Antibody to High Molecular Weight Kininogen (HMWK) In Stock
- Sandwich ELISA SEB805Hu ELISA Kit for High Molecular Weight Kininogen (HMWK) In Stock
- Sandwich CLIA SCB805Hu CLIA Kit for High Molecular Weight Kininogen (HMWK) In Stock
Organism species: Mus musculus (Mouse)
- Recombinant protein RPB805Mu01 Recombinant High Molecular Weight Kininogen (HMWK) In Stock
- Polyclonal antibody PAB805Mu01 Polyclonal Antibody to High Molecular Weight Kininogen (HMWK) In Stock
- High-sensitive ELISA HEB805Mu High Sensitive ELISA Kit for High Molecular Weight Kininogen (HMWK) In Stock
- Sandwich ELISA SEB805Mu ELISA Kit for High Molecular Weight Kininogen (HMWK) In Stock
Organism species: Rattus norvegicus (Rat)
- Recombinant protein RPB805Ra01 Recombinant High Molecular Weight Kininogen (HMWK) In Stock
- Polyclonal antibody PAB805Ra01 Polyclonal Antibody to High Molecular Weight Kininogen (HMWK) In Stock
- Labelled antibody LAB805Ra81 FITC-Linked Polyclonal Antibody to High Molecular Weight Kininogen (HMWK) In Stock
- Labelled antibody LAB805Ra71 Biotin-Linked Polyclonal Antibody to High Molecular Weight Kininogen (HMWK) In Stock
- Customized Service n/a CLIA Kit for High Molecular Weight Kininogen (HMWK) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for High Molecular Weight Kininogen (HMWK) ELISA Kit Customized Service Offer