Histone Cluster 1, H3j (HIST1H3J)

H3FJ; H3/j; H3 Histone Family Member J

Histone Cluster 1, H3j (HIST1H3J)
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures.HIST1H3J is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.Albig and Doenecke (1997) characterized a second cluster of 16 histone genes, including H3/j, located 2 Mb centromeric to the major histone gene cluster.

Organism species: Homo sapiens (Human)