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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
Huntingtin (HTT)
IT15; HD; Interesting Transcript 15
Huntingtin has no sequence homology with other proteins and is highly expressed in neurons and testes in humans and rodents. Huntingtin upregulates the expression of Brain Derived Neurotrophic Factor (BDNF) at the transcription level but the mechanism by which huntingtin regulated gene expression has not been determined. From immunohistochemistry, electron microscopy, and subcellular fractionation studies of the molecule, it has been found that huntingtin is primarily associated with vesicles and microtubules. These appear to indicate a functional role in cytoskeletal anchoring or transport of mitochondria. The Htt protein is involved in vesicle trafficking as it interacts with HIP1, a clathrin binding protein, to mediate endocytosis, the absorption of materials into a cell.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPH922Hu01 Recombinant Huntingtin (HTT) Customize
Antibodies MAH922Hu21 Monoclonal Antibody to Huntingtin (HTT) Customize
PAH922Hu01 Polyclonal Antibody to Huntingtin (HTT) Customize
Assay Kits SEH922Hu ELISA Kit for Huntingtin (HTT) In Stock
SCH922Hu CLIA Kit for Huntingtin (HTT) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPH922Mu01 Recombinant Huntingtin (HTT) In Stock
RPH922Mu02 Recombinant Huntingtin (HTT) Customize
Antibodies PAH922Mu01 Polyclonal Antibody to Huntingtin (HTT) In Stock
PAH922Mu02 Polyclonal Antibody to Huntingtin (HTT) Customize
MAH922Mu21 Monoclonal Antibody to Huntingtin (HTT) Customize
Assay Kits SEH922Mu ELISA Kit for Huntingtin (HTT) In Stock
SCH922Mu CLIA Kit for Huntingtin (HTT) Customize
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME
Proteins RPH922Ra01 Recombinant Huntingtin (HTT) Customize
Antibodies MAH922Ra21 Monoclonal Antibody to Huntingtin (HTT) Customize
PAH922Ra01 Polyclonal Antibody to Huntingtin (HTT) Customize
Assay Kits SEH922Ra ELISA Kit for Huntingtin (HTT) In Stock
SCH922Ra CLIA Kit for Huntingtin (HTT) Customize