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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4 (HCN4)
HCN4 encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15.
The HCN4 cDNA predicts a protein of 1,203 amino acids. HCN4 contains 6 putative transmembrane segments, a pore region, and a cyclic nucleotide-binding domain (CNBD). Northern blot and PCR analyses showed that HCN4 is expressed at heart ventricle and atrium.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPH925Hu01 Recombinant Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4 (HCN4) Customize
Antibodies PAH925Hu01 Polyclonal Antibody to Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4 (HCN4) Customize
MAH925Hu21 Monoclonal Antibody to Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4 (HCN4) Customize
Assay Kits SEH925Hu ELISA Kit for Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4 (HCN4) Customize
SCH925Hu CLIA Kit for Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4 (HCN4) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPH925Mu01 Recombinant Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4 (HCN4) Customize
Antibodies PAH925Mu01 Polyclonal Antibody to Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4 (HCN4) Customize
MAH925Mu21 Monoclonal Antibody to Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4 (HCN4) Customize
Assay Kits SEH925Mu ELISA Kit for Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4 (HCN4) Customize
SCH925Mu CLIA Kit for Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4 (HCN4) Customize
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME
Proteins RPH925Ra01 Recombinant Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4 (HCN4) Customize
Antibodies PAH925Ra01 Polyclonal Antibody to Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4 (HCN4) Customize
MAH925Ra21 Monoclonal Antibody to Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4 (HCN4) Customize
Assay Kits SEH925Ra ELISA Kit for Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4 (HCN4) Customize
SCH925Ra CLIA Kit for Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4 (HCN4) Customize