Inhibitory Subunit Of NF Kappa B Zeta (IkBz)
NFKBIZ; INAP; MAIL; IL-1 inducible nuclear ankyrin-repeat protein; Molecule possessing ankyrin repeats induced by lipopolysaccharide; NF-kappa-B inhibitor zeta
NF-kappa-B inhibitor zeta is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production.
Two transcript variants encoding different isoforms have been found for this gene.Involved in regulation of NF-kappa-B transcription factor complexes. Inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation.
Organism species: Homo sapiens (Human)
- Recombinant protein RPC249Hu01 Recombinant Inhibitory Subunit Of NF Kappa B Zeta (IkBz) In Stock
- Polyclonal antibody PAC249Hu01 Polyclonal Antibody to Inhibitory Subunit Of NF Kappa B Zeta (IkBz) In Stock
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Organism species: Mus musculus (Mouse)
- Recombinant protein RPC249Mu01 Recombinant Inhibitory Subunit Of NF Kappa B Zeta (IkBz) In Stock
- Polyclonal antibody PAC249Mu01 Polyclonal Antibody to Inhibitory Subunit Of NF Kappa B Zeta (IkBz) In Stock
- Sandwich ELISA SEC249Mu ELISA Kit for Inhibitory Subunit Of NF Kappa B Zeta (IkBz) In Stock
Organism species: Rattus norvegicus (Rat)
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