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ITEM PROTEIN ANTIBODY ASSAY KIT CELL
Inositol-1,4,5-Trisphosphate Receptor Type 1 (ITPR1)
IP3R; IP3R1; Insp3r1; SCA15; SCA16; Spinocerebellar Ataxia 15
ITPR1 encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene. Inositol 1,4,5-triphosphate is an intracellular second messenger produced by phospholipase C through a G protein-dependent mechanism. It releases calcium from endoplasmic reticulum by binding to specific receptors that are coupled to calcium channels. These receptors are abundant in neuronal and nonneuronal tissues. The neuronal form of the receptor is abundant in the cerebellum, particularly the perikaryon of the Purkinje cells.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME
Proteins RPE845Hu01 Recombinant Inositol-1,4,5-Trisphosphate Receptor Type 1 (ITPR1) Customize
Antibodies PAE845Hu01 Polyclonal Antibody to Inositol-1,4,5-Trisphosphate Receptor Type 1 (ITPR1) Customize
MAE845Hu21 Monoclonal Antibody to Inositol-1,4,5-Trisphosphate Receptor Type 1 (ITPR1) Customize
Assay Kits SEE845Hu ELISA Kit for Inositol-1,4,5-Trisphosphate Receptor Type 1 (ITPR1) Customize
SCE845Hu CLIA Kit for Inositol-1,4,5-Trisphosphate Receptor Type 1 (ITPR1) Customize
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME
Proteins RPE845Mu01 Recombinant Inositol-1,4,5-Trisphosphate Receptor Type 1 (ITPR1) Customize
Antibodies PAE845Mu01 Polyclonal Antibody to Inositol-1,4,5-Trisphosphate Receptor Type 1 (ITPR1) Customize
MAE845Mu21 Monoclonal Antibody to Inositol-1,4,5-Trisphosphate Receptor Type 1 (ITPR1) Customize
Assay Kits SEE845Mu ELISA Kit for Inositol-1,4,5-Trisphosphate Receptor Type 1 (ITPR1) Customize
SCE845Mu CLIA Kit for Inositol-1,4,5-Trisphosphate Receptor Type 1 (ITPR1) Customize
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME
Proteins RPE845Ra01 Recombinant Inositol-1,4,5-Trisphosphate Receptor Type 1 (ITPR1) Customize
Antibodies PAE845Ra01 Polyclonal Antibody to Inositol-1,4,5-Trisphosphate Receptor Type 1 (ITPR1) Customize
MAE845Ra21 Monoclonal Antibody to Inositol-1,4,5-Trisphosphate Receptor Type 1 (ITPR1) Customize
Assay Kits SEE845Ra ELISA Kit for Inositol-1,4,5-Trisphosphate Receptor Type 1 (ITPR1) Customize
SCE845Ra CLIA Kit for Inositol-1,4,5-Trisphosphate Receptor Type 1 (ITPR1) Customize