Insulin Like Growth Factor 2 mRNA Binding Protein 1 (IGF2BP1)
CRD-BP; CRDBP; IMP-1; IMP1; VICKZ1; ZBP1; IGF II mRNA Binding Protein 1; Coding region determinant-binding protein; Zipcode-binding protein 1
IMP1 contains 6 characteristic RNA-binding modules, including 2 N-terminal RRM domains and 4 central and C-terminal KH domains. It shares 59% amino acid identity with IMP2 and IMP3, 95% identity with chicken zipcode-binding protein, and 99% identity with mouse Crdbp. Immunocytochemical analysis of cultured cells showed a dynamic subcellular localization for IMP1 that was dependent upon the cell type, the degree of cell differentiation, and exposure of the cells to serum factors that differ between newborn and fetal calf serum. However, analysis of mouse embryos showed that expression of all 3 Imp transcripts peaked at embryonic day 12.5 and declined toward birth. RNA dot blot analysis detected moderate IMP1 expression in placenta and in all human fetal tissues of mixed first-trimester age examined.
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
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- Customized Service n/a Monoclonal Antibody to Insulin Like Growth Factor 2 mRNA Binding Protein 1 (IGF2BP1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Insulin Like Growth Factor 2 mRNA Binding Protein 1 (IGF2BP1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Insulin Like Growth Factor 2 mRNA Binding Protein 1 (IGF2BP1) CLIA Kit Customized Service Offer
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Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Insulin Like Growth Factor 2 mRNA Binding Protein 1 (IGF2BP1) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Insulin Like Growth Factor 2 mRNA Binding Protein 1 (IGF2BP1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Insulin Like Growth Factor 2 mRNA Binding Protein 1 (IGF2BP1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Insulin Like Growth Factor 2 mRNA Binding Protein 1 (IGF2BP1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Insulin Like Growth Factor 2 mRNA Binding Protein 1 (IGF2BP1) ELISA Kit Customized Service Offer