Integral Membrane Protein 2B (ITM2B)

ABRI; BRI; BRI2; BRICD2B; E25B; E3-16; FBD; Immature BRI2; Transmembrane protein BRI
Integral Membrane Protein 2B (ITM2B)
ITM2B or BRI2 is a gene located on chromosom 13. The gene is connected to Familial Danish Disease (FDD) and Familial British Disease (FBD) causing amyloid and pre-filbrillar effects similar to those seen in Alzheimers Disease (AD).
The BRI cDNA encodes a predicted protein of 266 amino acids. The first ATG is located 150 basepairs downstream of an in-frame TAG stop codon and has a classic Kozak consensus sequence. Hydropathy analysis indicated the presence of a putative single transmembrane-spanning domain between amino acids 52 and 74, indicating that this highly insoluble molecule is a type II integral transmembrane protein with the C-terminal part being extracellular. A potential N-glycosylation site was identified at asparagine-170.
Organism species: Homo sapiens (Human)
  • Protein RPL634Hu01Recombinant Integral Membrane Protein 2B (ITM2B)Customize
  • AntibodyPAL634Hu01Polyclonal Antibody to Integral Membrane Protein 2B (ITM2B)Customize
  • AntibodyMAL634Hu21Monoclonal Antibody to Integral Membrane Protein 2B (ITM2B)Customize
  • Assay KitSEL634HuELISA Kit for Integral Membrane Protein 2B (ITM2B)Customize
  • Assay KitSCL634HuCLIA Kit for Integral Membrane Protein 2B (ITM2B)Customize
Organism species: Mus musculus (Mouse)
  • Protein RPL634Mu01Recombinant Integral Membrane Protein 2B (ITM2B)Customize
  • AntibodyPAL634Mu01Polyclonal Antibody to Integral Membrane Protein 2B (ITM2B)Customize
  • AntibodyMAL634Mu21Monoclonal Antibody to Integral Membrane Protein 2B (ITM2B)Customize
  • Assay KitSEL634MuELISA Kit for Integral Membrane Protein 2B (ITM2B)Customize
  • Assay KitSCL634MuCLIA Kit for Integral Membrane Protein 2B (ITM2B)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPL634Ra01Recombinant Integral Membrane Protein 2B (ITM2B)Customize
  • AntibodyPAL634Ra01Polyclonal Antibody to Integral Membrane Protein 2B (ITM2B)Customize
  • AntibodyMAL634Ra21Monoclonal Antibody to Integral Membrane Protein 2B (ITM2B)Customize
  • Assay KitSEL634RaELISA Kit for Integral Membrane Protein 2B (ITM2B)Customize
  • Assay KitSCL634RaCLIA Kit for Integral Membrane Protein 2B (ITM2B)Customize
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