Speckled 110 kDa (SP110)
SP110; IIFI41; FI75; SP110 Nuclear Body Protein; Interferon Induced Protein 41, 30kDa; Transcriptional coactivator Sp110; Interferon-induced protein 41/75
SP110 is associated with the PML nuclear body, a macromolecular complex within the nucleus that is deployed to areas of active host or viral DNA replication, transcription, and repair. In addition to the regulation of gene transcription, the PML nuclear body is involved in other cellular processes such as apoptosis, cell cycle control, and the immune response.
The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified.
Organism species: Homo sapiens (Human)
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Organism species: Mus musculus (Mouse)
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Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Speckled 110 kDa (SP110) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Speckled 110 kDa (SP110) Monoclonal Antibody Customized Service Offer
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- Customized Service n/a CLIA Kit for Speckled 110 kDa (SP110) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Speckled 110 kDa (SP110) ELISA Kit Customized Service Offer