Interferon Regulatory Factor 8 (IRF8)
H-ICSBP; ICS-BP; ICSBP1; Interferon Consensus Sequence-Binding Protein 1
Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha; and IFN-beta;. IRF family proteins also control expression of IFN-alpha; and IFN-beta;-regulated genes that are induced by viral infection..
Mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP KO mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.
Organism species: Homo sapiens (Human)
- Recombinant protein RPB776Hu01 Recombinant Interferon Regulatory Factor 8 (IRF8) In Stock
- Polyclonal antibody PAB776Hu01 Polyclonal Antibody to Interferon Regulatory Factor 8 (IRF8) In Stock
- Customized Service n/a CLIA Kit for Interferon Regulatory Factor 8 (IRF8) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Interferon Regulatory Factor 8 (IRF8) ELISA Kit Customized Service Offer
Organism species: Mus musculus (Mouse)
- Recombinant protein RPB776Mu01 Recombinant Interferon Regulatory Factor 8 (IRF8) In Stock
- Active protein APB776Mu01 Active Interferon Regulatory Factor 8 (IRF8) In Stock
- Polyclonal antibody PAB776Mu01 Polyclonal Antibody to Interferon Regulatory Factor 8 (IRF8) In Stock
- Customized Service n/a CLIA Kit for Interferon Regulatory Factor 8 (IRF8) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Interferon Regulatory Factor 8 (IRF8) ELISA Kit Customized Service Offer
Organism species: Rattus norvegicus (Rat)
- Customized Service n/a Recombinant Interferon Regulatory Factor 8 (IRF8) Recombinant Protein Customized Service Offer
- Customized Service n/a Monoclonal Antibody to Interferon Regulatory Factor 8 (IRF8) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Interferon Regulatory Factor 8 (IRF8) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Interferon Regulatory Factor 8 (IRF8) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Interferon Regulatory Factor 8 (IRF8) ELISA Kit Customized Service Offer