Interleukin 1 Epsilon (IL1e)
IL1F6; IL36a; FIL1; FIL1(EPSILON); FIL1E; IL-1F6; IL1(EPSILON); Interleukin 36, Alpha; Interleukin 1 Family, Member 6
The cytokine interleukin-1 (IL1) elicits a wide array of biologic activities that initiate and promote the host response to injury or infection by activating a set of transcription factors, including NFKB and AP1, which in turn induce production of effectors of the inflammatory response. By searching an EST database for sequences resembling IL1 and probing a human genomic library, Smith et al. (2000) identified a cDNA encoding IL1F6, which they designated FIL1-epsilon. The deduced 158-amino acid protein, like FIL1-delta, contains neither a signal peptide nor a prodomain. It shares 48% sequence identity with FIL1-eta. PCR analyses detected expression in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. Modeling indicated that FIL1-epsilon has a conserved 12-stranded beta-trefoil structure.
Organism species: Homo sapiens (Human)
- Recombinant protein RPE843Hu01 Recombinant Interleukin 1 Epsilon (IL1e) In Stock
- Active protein APE843Hu01 Active Interleukin 1 Epsilon (IL1e) In Stock
- Monoclonal antibody MAE843Hu21 Monoclonal Antibody to Interleukin 1 Epsilon (IL1e) In Stock
- Polyclonal antibody PAE843Hu01 Polyclonal Antibody to Interleukin 1 Epsilon (IL1e) In Stock
- Sandwich CLIA SCE843Hu CLIA Kit for Interleukin 1 Epsilon (IL1e) In Stock
- Sandwich ELISA SEE843Hu ELISA Kit for Interleukin 1 Epsilon (IL1e) In Stock
Organism species: Mus musculus (Mouse)
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Organism species: Rattus norvegicus (Rat)
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