Isoprenoid Synthase Domain Containing Protein (ISPD)

Nip; Notch1-Induced Protein; 4-Diphosphocytidyl-2C-Methyl-D-Erythritol Synthase Homolog; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein
Isoprenoid Synthase Domain Containing Protein (ISPD)
A hypothetical gene with similarity to the ispD gene of Escherichia coli was cloned from Arabidopsis thaliana cDNA. The ORF of 909 bp specifies a protein of 302 amino acid residues. The cognate chromosomal gene consists of 2,071 bp and comprises 11 introns with a size range of 78–202 bp. A fragment comprising amino acid residues 76–302 was expressed in a recombinant E. coli strain.  
Numb and Notch signalling pathways are vitally important in cell fate and differentiation. The outcome of these signalling processes is determined by a delicate balance between opposing effects of Notch and Numb. Imbalance in Numb/Notch regulation was implicated in aberrant differentiation programme and epithelial cancer progression and metastasis.

Organism species: Homo sapiens (Human)
  • Protein RPT839Hu01Recombinant Isoprenoid Synthase Domain Containing Protein (ISPD)Customize
  • AntibodyPAT839Hu01Polyclonal Antibody to Isoprenoid Synthase Domain Containing Protein (ISPD)Customize
  • AntibodyMAT839Hu21Monoclonal Antibody to Isoprenoid Synthase Domain Containing Protein (ISPD)Customize
  • Assay KitSET839HuELISA Kit for Isoprenoid Synthase Domain Containing Protein (ISPD)Customize
  • Assay KitSCT839HuCLIA Kit for Isoprenoid Synthase Domain Containing Protein (ISPD)Customize
Organism species: Mus musculus (Mouse)
  • Protein RPT839Mu01Recombinant Isoprenoid Synthase Domain Containing Protein (ISPD)Customize
  • AntibodyPAT839Mu01Polyclonal Antibody to Isoprenoid Synthase Domain Containing Protein (ISPD)Customize
  • AntibodyMAT839Mu21Monoclonal Antibody to Isoprenoid Synthase Domain Containing Protein (ISPD)Customize
  • Assay KitSET839MuELISA Kit for Isoprenoid Synthase Domain Containing Protein (ISPD)Customize
  • Assay KitSCT839MuCLIA Kit for Isoprenoid Synthase Domain Containing Protein (ISPD)Customize
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