Kelch Like Protein 23 (KLHL23)

KLHL23, Contains 1 BACK (BTB/Kelch associated) domain. Contains 1 BTB (POZ) domain. Contains 6 Kelch repeats. Kelch proteins (and Kelch-like proteins) are a widespread group of proteins that contain multiple Kelch motifs. The kelch domain generally occurs as a set of five to seven kelch repeats that form a β-propeller tertiary structure. Kelch-repeat β-propellers are generally involved in protein-protein interactions, though the large diversity of domain architectures and limited sequence identity between kelch motifs make characterisation of the kelch superfamily difficult. The function of Kelch proteins is unknown. However they are commonly seen to associate with actin tails.The first Kelch protein (from which this family derives its name) was isolated from Drosophila. It has also been isolated in many other animals, bacteria, fungi, and even virus.