Keratinocyte Associated Protein 2 (KRTCAP2)

Keratinocyte Associated Protein 2 belongs to the KRTCAP2 family. Expressed in skin, heart, placental, liver, skeletal muscle, kidney, pancreas, keratinocytes and dermal fibroblasts.Component of the oligosaccharyltransferase (OST) complex. OST seems to exist in different forms which contain at least RPN1, RPN2, OST48, DAD1, OSTC, KRTCAP2 and either STT3A or STT3B.

OST can form stable complexes with the Sec61 complex or with both the Sec61 and TRAP complexes. Keratinocyte differentiation-associated protein is a protein encoded by the KRTDAP gene.May act as a soluble regulator of keratinocyte differentiation. May play an important role in embryonic skin morphogenesis.