Killer Cell Lectin Like Receptor Subfamily H, Member 1 (KLRH1)
Gm156
NK cells have the ability to recognize and kill MHC-mismatched hemopoietic cells. Expression cloning revealed that each monomer consisted of 231 aa with limited homology to other previously characterized killer cell lectin-like receptors (KLRs). This glycoprotein therefore constitutes a novel KLR branch, and it has been termed KLRH1. A gene in the central region of the natural killer gene complex on rat chromosome 4 encodes KLRH1. A mouse homolog appears to be present as deduced from analyses of genomic trace sequences. The function of KLRH1 is unknown, but it contains an immunoreceptor tyrosine-based inhibitory motif, suggesting an inhibitory function. The MHC haplotype of the host appears to influence KLRH1 expression, suggesting that it may function as an MHC-binding receptor on subsets of NK cells and T lymphocytes.
Organism species: Mus musculus (Mouse)
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Organism species: Rattus norvegicus (Rat)
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- Customized Service n/a Monoclonal Antibody to Killer Cell Lectin Like Receptor Subfamily H, Member 1 (KLRH1) Monoclonal Antibody Customized Service Offer
- Customized Service n/a Polyclonal Antibody to Killer Cell Lectin Like Receptor Subfamily H, Member 1 (KLRH1) Polyclonal Antibody Customized Service Offer
- Customized Service n/a CLIA Kit for Killer Cell Lectin Like Receptor Subfamily H, Member 1 (KLRH1) CLIA Kit Customized Service Offer
- Customized Service n/a ELISA Kit for Killer Cell Lectin Like Receptor Subfamily H, Member 1 (KLRH1) ELISA Kit Customized Service Offer