Lamin B Receptor (LBR)

DHCR14B; LMN2R; PHA; Integral nuclear envelope inner membrane protein
Lamin B Receptor (LBR)
Lamin-B receptor is a protein  belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
It is phosphorylated by different protein kinases in interphase when the membrane is associated with these structures. Phosphorylation of LBR and HP1 proteins may be responsible for some of the alterations in chromatin organization and nuclear structure which occur at various times during the cell cycle.
Organism species: Homo sapiens (Human)
  • Protein RPC577Hu01Recombinant Lamin B Receptor (LBR)Customize
  • AntibodyPAC577Hu01Polyclonal Antibody to Lamin B Receptor (LBR)Customize
  • AntibodyMAC577Hu21Monoclonal Antibody to Lamin B Receptor (LBR)Customize
  • Assay KitSEC577HuELISA Kit for Lamin B Receptor (LBR)Customize
  • Assay KitSCC577HuCLIA Kit for Lamin B Receptor (LBR)Customize
Organism species: Mus musculus (Mouse)
  • Protein RPC577Mu01Recombinant Lamin B Receptor (LBR)Customize
  • AntibodyPAC577Mu01Polyclonal Antibody to Lamin B Receptor (LBR)Customize
  • AntibodyMAC577Mu21Monoclonal Antibody to Lamin B Receptor (LBR)Customize
  • Assay KitSEC577MuELISA Kit for Lamin B Receptor (LBR)Customize
  • Assay KitSCC577MuCLIA Kit for Lamin B Receptor (LBR)Customize
Organism species: Rattus norvegicus (Rat)
  • Protein RPC577Ra01Recombinant Lamin B Receptor (LBR)Customize
  • AntibodyPAC577Ra01Polyclonal Antibody to Lamin B Receptor (LBR)Customize
  • AntibodyMAC577Ra21Monoclonal Antibody to Lamin B Receptor (LBR)Customize
  • Assay KitSEC577RaELISA Kit for Lamin B Receptor (LBR)Customize
  • Assay KitSCC577RaCLIA Kit for Lamin B Receptor (LBR)Customize
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