Lectin, Mannose Binding 1 Like Protien (LMAN1L)

ERGL has 1 possible glycosylation site and 2 possible intracellular phosphorylation sites. Weaker but distinct 1.8- and 2.0-kb transcripts were detected in prostate, and a 1.8-kb transcript was detected in spleen. RNA dot blot analysis showed strongest ERGL expression in prostate, spleen, salivary gland, and cardiac atrium.

In situ hybridization detected ERGL in normal and neoplastic prostate epithelial cells, in acinar and duct epithelial cells of salivary gland, in neurons and astrocytes of cerebral cortex, in Purkinje cells of cerebellum, in motor neurons of the spinal cord ventral horn, and in marginal zones of B-cell follicles in spleen. Diffuse ERGL expression was detected in cardiac atrial muscle sarcoplasm and in isolated subendocardial cells, but not in cardiac ventricles.