Leucine, Glutamate And Lysine Rich 1 (LEKR1)

Chromosome 3 is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells.
Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1,cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B.Marfan syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.