Long Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 4 (LPLUNC4)

LPLUNC4 was unique among the PLUNC family proteins that we previously described, as it was not complete at the N-terminal end. These sequences were subsequently mapped onto the mouse and rat genome sequences to identify the intron/exon arrangement. This information was used to generate a complete open reading frame for both the mouse and rat genes. This information was then used to predict the complete human LPLUNC4 gene. The LPLUNC4 gene contains a very small third exon (63bp) compared to all of the other PLUNC family genes as well as a large additional exon, term exon 3b. Subsequently, the sequence of human LPLUNC4 was confirmed by a complete cDNA sequence within the patent divison of Genbank.